Fondazione IRCCS Istituto Neurologico Carlo Besta


Fondazione IRCCS Istituto Neurologico Carlo Besta


Via Celoria 11, 20133 Milano Italy




Adult and pediatric neurology and neurosurgery


+39 02 2394 2335 – +39 02 2394 2025


Fabrizio Tagliavini

The Carlo Besta Neurological Institute was founded in 1918, recognized by the Italian Ministry of Health as a Research Hospital (IRCCS) for “Diseases of the Nervous System of Adults and Children” in 1978, and transformed into a Public Foundation in 2006.

The Institute is one of the major national and international research hospitals in the areas of neurology, child neurology and neurosurgery, and is a reference center not only for highly prevalent diseases for which it excels in diagnosis, treatment and long-term care, but also in the field of rare and complex disorders that require diagnostic skills using advanced technological approaches and highly specialized continuing education. Since 2017, the Institute is part of the central hub of the University of Milan.

As a leading centre for rare diseases, it participates in five European Reference Networks: Neurological Diseases (ERN-RND), Epilepsies (ERN EpiCARE), Neuromuscular Diseases (ERN EURONMD), Adult Cancer – Solid Tumors (ERN EURACAN), and Rare Craniofacial Anomalies (ERN CRANIUM).

The strong integration of clinical and research activities is supported by a matrix organization model, with 5 Management Departments (Clinical Neuroscience, Pediatric Neuroscience, Neurosurgery, Clinical Research and Development, Diagnostics and Technology) and 8 Functional Departments dedicated to specific areas of pathology (Degenerative Diseases, Movement Disorders, Immunological Disorders, Cerebrovascular Diseases, Epilepsies, Tumors, Pain, Rare Diseases). The Institute has 180 beds for hospitalization and a day service area. Every year there are more than 5,500 admissions and about 100,000 highly specialized outpatient visits.

The mission of the Institute is to understand the pathogenesis of neurological diseases and develop advanced diagnostic technologies (in particular neuroimaging, neurophysiology and genomics) and innovative therapies through experimental processes, with the ultimate goal of offering patients the best treatment opportunities.

The scientific activity is carried out by 200 researchers, and translates into about 150 clinical trials and over 350 peer-reviewed publications per year. The institute has two biobanks and biorepositories of biological material for major neurological diseases, with a total of about 200,000 samples. It is coordinator or partner of several national and international research projects, and is a member of various national and international disease networks.